The novel is primarily set in the upper New York wilderness, detailing the transport of the two daughters of Colonel Munro, Alice and Cora, to a safe destination at Fort William Henry. Among the caravan guarding the women are the frontiersman Natty Bumppo, Major Duncan Heyward, and the Indians Chingachgook and Uncas, the former of whom is the novel's title character. These characters are sometimes seen as a microcosm of the budding American society, particularly with regards to their racial composition.