The global aspects of the problem of evolution equations in general relativity are examined. Central to the work is a revisit of the proof of the global stability of Minkowski space, as presented by Christodoulou and Klainerman (1993). The focus, therefore, is on a new self-contained proof of the main part of that result which concerns the full solution of the radiation problem in vacuum for arbitrary asymptotic flat initial data sets. This important monograph is aimed at researchers and graduate students in mathematics, mathematical physics, and physics working in the area of general relativity.