H.G. Wells (1866-1946) wrote some of the great classics of speculative fiction in English, including The Island of Doctor Moreau (1896), which might be said to be about unholy genetics. The work's biological and sociopolitical ideas are still current (such were the range and depth of Wells' ideas).

Wells continued to work on Doctor Moreau for nearly thirty years after its initial publication in London (the New York first edition added a subtitle A Possibility), finally letting go of the work after the publication of the Atlantic Edition in 1924. Annotated by the premier Wellsian scholar, this is an exhaustive critical edition, examining the historical, medical, philosophical and literary contexts of the story.