Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.

Numerous images of plants and chemical structural formulas complete the book, as well as extensive references for further reading.

The multivolume reference is an essential resource for physicians, veterinarians, pharmacists, chemists, biochemists, food chemists and biologists, for students in the relevant fields, and maybe for interested laymen.

All aspects of natural toxins based on the latest scientific knowledge are included:

• All aspects of the toxicology of all living organisms and natural foods, chemistry, action mechanisms, symptoms of intoxications.
• The only book arranged on a strictly scientific base according to the biogenetic origin and chemical structure.

Natural Poisons and Venoms in 5 Volumes:

Volume 1: Plant Toxins: Terpenes and Steroids 2023, ISBN 978-3-11-072472-1

Volume 2: Plant Toxins: Polyketides, Phenylpropanoids and Further Compounds 2024, ISBN 978-3-11-072851-4

Volume 3: Plant Toxins: Alkaloids and Lectins 2025, ISBN 978-3-11-112740-8

Volume 5: Fungal and Microbial Toxins 2025, ISBN 978-3-11-072856-9

Dangerous, dark and difficult to detect, poisons have been a common character in literature from ancient times to the modern day. Their ability to perform deadly deeds at a distance is a common device for creating dramatic tension and playing on our real life fears. But what is fact and what is pure fiction?

From Shakespeare and Dickens to Hugo and Poe, the macabre world of literary poisonings is as large as it is fascinating. Utilising real forensic science Poisonous Tales explores the real science inspiring the toxins and tinctures in our favourite works. Could a poison really mimic death in Romeo and Juliet? What is the cause of the mad Hatter's malady in Alice in Wonderland? And could a stone from the stomach of a goat really have been used as an antidote in Harry Potter and the Half-Blood Prince? Through these and many more 'cases' we discover the captivating truth in the texts and how real-life tragedies can replicate themselves in fiction.

Fourteen stories. Fourteen more poisons. Just because it's fiction doesn't mean it's all made-up ...

Agatha Christie is renowned for her captivating plots and creative ways of killing off ill-fated victims. And what better way to add intrigue to a story than poison? The surreptitious ways they can be administered and the characteristic symptoms they produce make these killer chemicals the ideal method of murder in a 'whodunit'. Christie perfected the use of poisons in her plots; her deft and varied use of toxic substances is one of her great strengths as a writer. But how is it that some compounds prove so fatal, and in such tiny amounts?

The follow up to Kathryn Harkup's best-selling A is for Arsenic, V is for Venom is a compelling exploration of Christie's use of poisons and her extensive chemical knowledge. Featuring fourteen more poisons from the works of Agatha Christie, this book investigates the science behind the deadly substances, the history of their use in real-life murder cases, and how feasible was it to obtain, administer and detect these poisons in Christie's time and today. Combining Christie's murder mysteries, chemical science and true crime, V is for Venom is a celebration of the use of science by the undisputed Queen of Crime.

Biogenic toxins are fascinating natural products characterized by an enormous diversity of chemical structures and pharmacological activities. They not only pose hazards to humans and animals, but they are important components in the interplay of substances and living beings in nature and, moreover, important sources for new drugs.

Numerous images of plants and chemical structural formulas complete the book, as well as extensive references for further reading.

The multivolume reference is an essential resource for physicians, veterinarians, pharmacists, chemists, biochemists, food chemists and biologists, for students in the relevant fields, and maybe for interested laymen.

All aspects of natural toxins based on the latest scientific knowledge are included:

• All aspects of the toxicology of all living organisms and natural foods, chemistry, action mechanisms, symptoms of intoxications.
• The only book arranged on a strictly scientific base according to the biogenetic origin and chemical structure.

Natural Poisons and Venoms in 5 Volumes:

Volume 2: Plant Toxins: Polyketides, Phenylpropanoids and Further Compounds 2024, ISBN 978-3-11-072851-4

Volume 3: Plant Toxins: Alkaloids and Lectins 2025, ISBN 978-3-11-112740-8

Volume 4: Animal Toxins 2023, ISBN 978-3-11-072854-5

Volume 5: Fungal and Microbial Toxins 2025, ISBN 978-3-11-072856-9

Historia elemental de las drogas propone un documentado y ameno recorrido hist rico por la evoluci n de los diversos tipos de droga y sus usos, desde los ritos religiosos para acceder a la verdad revelada en determinadas sociedades hasta la invasi n del crack y las drogas de dise o, desde las guerras del opio hasta el estallido de la psiquedelia. Esta s ntesis de la monumental Historia general de las drogas analiza la evoluci n de las actitudes ante las drogas a lo largo de la historia; su utilizaci n con fines religiosos, terap uticos o meramente hedonistas; la reacci n del Estado y los problemas que conlleva la prohibici n, la anatemizaci n y la persecuci n policial... La obra aporta un enorme caudal de informaci n y plantea un acercamiento al universo de las drogas que huye de t picos, banalizaciones y visiones simplistas. Afirma Escohotado en el pr logo que aunque hasta hace poco fuese un campo reservado al sensacionalismo period stico, o a abstrusos manuales de toxicolog a, la particular historia de las drogas ilumina la historia general de la humanidad con una luz propia, como cuando abrimos una ventana hasta entonces cerrada al horizonte y las mismas cosas aparecen bajo una perspectiva nueva.

Toxicology - the study of the adverse effects of chemicals on living organisms is the cornerstone to all aspects of chemical safety and knowledge of the subject is needed in a wide spectrum of fields from the chemical industry to medicine, emergency services, forensics, and regulatory science. Toxicology involves the study of symptoms, mechanisms, treatments and detection of poisoning ... especially the poisoning of people.

The many problems arising from a poor understanding of toxicology and its applications in hazard communication and chemical safety motivated the author's training courses and webinars, leading to this valuable book.

Providing a practical and accessible guide, A Practical Guide to Toxicology and Human Health Risk Assessment enables readers to quickly build up knowledge and understanding of toxicology and its use in hazard identification, which is a fundamental part of chemical risk assessment. The book also covers current toxicological testing strategies and the use of physicochemical test data in hazard identification and exposure assessment.

Examples are provided throughout the book to highlight important issues along with a summary of the key points that have been covered in each of the respective chapters. The book concludes with a listing of online resources on toxicology and risk assessment.

This text covers the basic principles of toxicology, including the nature, effects, and detection of toxic substances. It explores the mechanisms of toxicity, including the ways in which toxic substances interact with living organisms. The book also examines the different types of toxic agents and their effects on human health and the environment. It is an essential resource for toxicologists, public health officials, and environmental scientists seeking to understand the impact of toxic substances on human health and the environment.

Since the 1920's, modern science has known about the dangers of fluoride poisoning Sadly, this truth is continually hidden from the public. Here is the effort of one man to warn the world: Dr. Leo Spira, M.D., Ph.D. (Medicine). His book, The Drama of Fluorine is herein reproduced, and edited only to add understanding and definition and to republish and make more available and searchable, the contents in its electronic form. There is nothing removed from the original. The book details his journey to track down what was causing such great harm to so many in his community when he lived in London, England in the 1920's. It was traced to fluorine as part of the production of aluminum which was used to make cooking utensils. His revelations were the first and he worked hard to get the news out. But, though the discovery was of great import and affected the health of the public at large, he immediately encountered censorship and suppression of truth. As is often the case when a discovery inadvertently indicates that a sector of business has faults directly detrimental to a population's health, research was stolen, truth was suppressed and experts were coerced or paid to lie to the public. The bulk of the work tells of his in-depth research, over decades, on the subject matter. It's very detailed and specific and the results are concrete. The data presented is helpful to medical professionals who are encountering the variety of symptoms caused by fluorine poisoning. The Editor, himself, suffered from such poisoning and recovered after finding out the cause. The latter led him to research and find Dr. Spira's book. His own story and insights can be found in his own book, How My Eyes Were Healed Naturally, and Yours Can Too.

Marine Bivalve Mollusks and Emerging Pollutants: Toxicological Impacts provides the most updated and comprehensive knowledge of the toxicological impacts of a variety of emerging pollutants on marine bivalve mollusk species. In addition to synthesizing recent toxicological findings, the book also discusses toxification mechanisms, current challenges, and future research prospects. Written by international experts, this book assesses new advances in the toxicological impacts of pollutants, including microplastics, bromide flame retardants, nanomaterials, pharmaceutical residues, personal care products, pesticides, and perfluorinated compounds. In addition, it details how these can affect reproduction, embryonic development, metabolism, and immune systems of marine bivalves. Behavioral responses and neuroendocrine regulation is also discussed. Toxification mechanisms are interpreted at both physiological and molecular levels. The book concludes with current research and environmental challenges and potentials for further, future study techniques.

With the expansion of human settlements and the environmental changes brought about by human activity and pollutants, toxicology and risk assessment of amphibian species has become increasingly of interest to toxicologists involved in environmental research.

This book focuses specifically on environmental risk assessment in premetamorphic stages and adults of amphibians. Amphibian ecotoxicology is not totally understood in scientific research and as such environmental risk assessment in these vertebrates is an area of rapidly growing interest. It has the potential to answer some of the questions regarding risks to our environment.

An ideal companion, this book will be useful to toxicologists and ecologists investigating risk assessment in the environments of amphibians, while also of interest to those working in conservation biology, biological invasion, biocontrol and habitat management.

This book Modern Toxicology and its Developments provides an overview of toxicology, including the description of the essential theories, technologies and tools. Different examples of toxicology applications in human health are thoroughly discussed in this text. Toxicology is a scientific subject that overlaps with biology, chemistry, pharmacology, and medicine and entails the study of the harmful effects of chemical compounds on living organisms as well as the practice of detecting and treating toxins and toxicants exposures. Toxicology actively assists cancer research since some toxins may be used as medications to destroy tumor cells. Ribosome-inactivating proteins, which have been studied in leukemia treatment, are a classic example of this.This textbook presents new students and researchers with an easy-to-understand, complete overview and understanding of toxicological ideas, recommendations, and, in particular, complex instrumentation methods. This offers an authoritative perspective on the science and its future. The knoledge of toxicity and mechanisms of toxicity play an important role in different industries including pharmaceuiticals, food industry, agriculture, chemical industry. This handbook also illustrates the health impacts of metals, petroleum products, paper and pulp industry waste, air pollutants, and animal poisons. This book is equally beneficial for students, teachers and researchers in the field of toxicology. Moreover, this book is also a good resource for environmentalists and policy makers.

Neurotransmitters are usually considered to be endogenous substances that are released from neurons, act on receptor sites that are typically present on membranes of postsynaptic cells and produce a functional change in the properties of the target cell. They are essential features of the nervous systems of all animals, and numerous chemicals can act as neurotransmitters either intentionally (e.g. pesticides) or unintentionally (neurotoxins). The most common forms of neurotoxicity are the death of neurons, degeneration of axons, damage to glial cells and interference with the axonal membrane or neurotransmission. Important neurotoxins are found among pesticides, metals, solvents, natural substances, and industrial chemicals. Environmental chemicals may also contribute to the pathology of neurodevelopmental, neuropsychiatric, and neurodegenerative disorders. Neurotransmitters and Toxicology will be particularly appealing to toxicologists interested in neurotoxicology in various sub-disciplines, as well as neuro-chemists interested in pathology and disease mechanisms associated with neurotoxicants.

Das Buch Chemometrics and Cheminformatics in Aquatic Toxicology befasst sich mit den bestehenden und neu auftretenden Problemen der Verschmutzung der aquatischen Umwelt durch verschiedene metallische und organische Schadstoffe, insbesondere Industriechemikalien, Pharmazeutika, Kosmetika, Biozide, Nanomaterialien, Pestizide, Tenside, Farbstoffe und viele weitere. Es werden verschiedene chemometrische und cheminformatische Instrumente für Laien beschrieben mitsamt ihrer Anwendung auf die Analyse und Modellierung der Toxizitätsdaten von Chemikalien in Bezug auf unterschiedliche aquatische Organismen.

Eine Reihe von Datenbanken zur aquatischen Toxizität sowie chemometrische Softwaretools und Webserver werden vorgestellt und praktische Beispiele für die Modellentwicklung gegeben, einschlie lich der entsprechenden Abbildungen. Darüber hinaus enthält das Werk Fallstudien und Literaturberichte, um das Verständnis des Themas abzurunden. Au erdem lernen die Leserinnen und Leser Werkzeuge und Protokolle wie maschinelles Lernen, Data Mining sowie Methoden des QSAR-basierten und ligandenbasierten chemischen Designs kennen.

Darüber hinaus bietet das Werk:
* Eine umfassende Einführung in chemometrische und cheminformatische Instrumente und Techniken, insbesondere maschinelles Lernen und Data Mining
* Eine Darstellung von Datenbanken zur aquatischen Toxizität, chemometrischen Softwaretools und Webservern
* Praktische Beispiele und Fallstudien zur Verdeutlichung und Veranschaulichung der im Buch enthaltenen Konzepte
* Eine kompakte Erläuterung der chemometrischen und cheminformatischen Instrumente sowie ihrer Anwendung auf die Analyse und Modellierung von Toxizitätsdaten

Chemometrics and Cheminformatics in Aquatic Toxicology ist ideal für Forschende und Studierende der Chemie sowie der Umwelt- und Pharmawissenschaften und sollte auch in den Bibliotheken von Fachleuten in der chemischen Industrie sowie Aufsichtsbehörden, die sich mit Chemometrie beschäftigen, einen Platz finden.

Green toxicology is an integral part of green chemistry. One of the key goals of green chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in green chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of green chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating green toxicology principles into their work.

Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.

Forensic Investigation of Clandestine Laboratories, Second Edition is fully updated to address all aspects of the forensic investigation of clandestine laboratories. While, the first edition focused on the domestic clandestine manufacture of contraband substances, this edition expands the scope to more fully address the clandestine manufacture of explosives that have become a threat that is global in nature.

In clandestine laboratory operations, equipment is often simple, household chemical products are utilized, and the education of the operators basic. In fact, most of the time these elements individually are perfectly legal to sell and possess. However, the combination of all these elements is what becomes the scene of illicit activity and a criminal operation. In response to the increase in use of homemade explosive mixtures by terrorists, both domestically and internationally, the section clandestine manufacture of explosives is greatly enhanced. Topics are presented in a manner which, while detailed, will not compromise the tactics, techniques, or procedures utilized by law enforcement and military personnel in their ability to combat the clandestine manufacture of contraband substances and the battle against domestic and international terrorism.

Key features:

- Examines tell-tale signs to look for in recognizing a clandestine lab

- Outlines how to safely process the site of a clandestine lab

- Details how to analyze collected evidence in the examination laboratory

- Provides guidelines as to what to derive from the physical evidence

- Offers specific tactics to effectively present the opinions associated with evidence that has been collected during the investigation in a written report, military style briefing or to a jury in a legal proceeding.

Forensic Investigation of Clandestine Laboratories, Second Edition guides the reader through the process of recognizing these illegal manufacturing operations. Then it examines the methods as to how to compile the volume of associated evidence into a package that can be presented in a court of law, or to military commanders for decisive action. It is an invaluable resource, that will prove useful to chemistry lab technicians, forensic investigators, fire and first responder professionals, military personnel, police investigative agencies and narcotics units, and lawyer trying cases involving clandestine labs.

Microplastics in Urban Water Management

Enables readers to understand the true occurrence and fate of microplastics in drinking water, wastewater and sludge, and receiving water

Microplastics in Urban Water Management focuses on the occurrence, fate, effect, and removal of microplastics in the urban water management systems, summarizing relevant methods for enhancing microplastics removal and degradation, providing comprehensive data from source to sink (including occurrence and fate of microplastics in urban water management), and covering practical applications, which are expected to provide some theoretical guidance for controlling or mitigating microplastics pollution and its environmental risks.

The work also includes detailed multidisciplinary information on the way in which microplastics behave in urban water management, plus recent advances of nanoplastics, i.e., nano-sized microplastics, in the aquatic environment.

In Microplastics in Urban Water Management, readers can expect to find detailed information on sample topics such as:

• Techniques for microplastics detection, including sample collection, purification, identification, and quantitation, plus the definition, emergence, occurrence, and removal of microplastics
• Elements of microplastics in wastewater treatment plants; for instance, the ecotoxicological effect on the biological treatment of wastewater and sludge
• Why the discharge of microplastics from wastewater treatment plants is the important source of microplastics in the receiving waters
• Potential environmental risks of microplastic contamination in receiving water systems and evidence that microplastics can absorb, collect and transport environmental contaminants as vectors

For practicing toxicologists, biologists, environmental and chemical engineers, and ecology professionals, as well as researchers and graduate students in these disciplines, Microplastics in Urban Water Management is an essential all-in-one guide to understanding the current state of microplastics in our world and potential solutions for the future.

This set summarizes and discusses scientific studies that have analyzed the effect of nanoparticles on the immune system in humans and animals. Both volumes are also available individually: Vol 1: ISBN 978-3-11-065407-3 and Vol 2: 978-3-11-065408-0

Environmental issues such as ozone layer depletion, overpopulation, biodiversity loss, global warming, natural resource depletion, and so on affect every organism on the planet somehow. Environmental biotechnology applications can help to protect and restore the quality of the environment. The goal is to use biotechnology with other technologies and safety procedures to prevent, arrest, and reverse environmental degradation. Environmental biotechnology is one of the most rapidly expanding and practically useful scientific fields. Biochemistry, physiology and genetic research of microorganisms can be converted into commercially available technologies for reversing and preventing further deterioration of the earth's environment. Solid, liquid, and gaseous wastes can be altered either by recycling new by-products or by purifying to make the end product less harmful to the environment. Biotechnology for Toxic Remediation and Environmental Sustainability discusses the removal of pollutants by absorption techniques and recycling wastewater into valuable by-products and biofuels by microorganisms. Moreover, this book also addresses corrosion prevention by green inhibitors, uses electrochemical systems for renewable energy and waste recycling using microbes, and recent food safety and security trends in the food microbiome. On the other hand, this book also discusses therapy and treatments against antibiotic-resistant bacteria, anti-cancer and pharmacological properties of thymoquinone and preventive properties of zinc nanoparticles against stress-mediated apoptosis in epithelial cells.

Features

• Covers all aspects of Biotechnological application in the environment
• Discusses sustainable technology for the wastewater treatment and value-added products from wastewater
• Focuses on research activities Green corrosion inhibitors, bio-electrochemical systems, food safety and security, and antimicrobial resistance

The book is a valuable resource for the undergrad and graduate students, doctoral and post-doctoral scholars, industrial personnel, academicians, scientists, researchers, and policymakers involved in understanding and implementing applications of biotechnology for environmental toxic remediation.

With the expansion of human settlements and the environmental changes brought on by human activity and pollutants, toxicology and risk assessment of bird and reptile species is becoming increasingly of interest to toxicologists involved in environmental research. This book focuses specifically on environmental risk assessment in non-conventional bird and reptile species.

Bird and Reptile Species in Environmental Risk Assessment Strategies will be an ideal companion to toxicologists and ecologists interested in risk assessment in the environments of birds and reptiles, particularly those with an interest in the impact introduced by human activity. The book will also be of interest to those working in conservation biology, biological invasion, biocontrol and habitat management.