As Dr. Nathan Bryan clearly points out, there's one miracle molecule in your body that is largely responsible for your health and longevity...NITRIC OXIDE. -Lou Ignarro, 1998 Nobel Prize Winner in Physiology or Medicine

The Secret of Nitric Oxide by Dr Nathan Bryan may be one of the most important books that you will ever read... -Mark C. Houston, M.D., M.S., M.Sc., Director, Hypertension Institute and Vascular Biology, Saint Thomas Hospital

Dr Bryan masterfully unveils the life-changing potential of nitric oxide, from its Nobel Prize-winning discovery to its transformative role in health and disease... -Robert Lufkin M.D., NYT bestselling author of Lies I Taught In Medical Schooland medical school professor

I enthusiastically endorse this book and urge all who care about health and healthy longevity to read it and incorporate this knowledge into your life... -Felice Gersh, M.D., Medical Director, Integrative Medical Group of Irvine

The remarkable discovery of the molecule nitric oxide or NO back in the early 1980s revolutionized vascular biology and the understanding of chronic disease. Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad won the 1998 Nobel Prize in Physiology or Medicine for their discoveries about nitric oxide. Several years later, one man and his discoveries cracked the code on developing a solid dose form of nitric oxide gas as an oral delivery and also a dual-chamber delivery for topical applications. This book will take the reader through the early life of Dr. Bryan through his education and research that led to these important discoveries and will inspire, motivate and encourage others to follow their dreams and not give up even when it seems the cards are stacked against you.

Product Description Eighty-one million Americans have cardiovascular disease, the arterial damage that leads to the heart attacks and strokes that account for 36 percent of all deaths in the U.S. But few people know that by boosting the body's levels of a single molecule--nitric oxide (NO)--you can help prevent, control and even reverse cardiovascular disease.

In this groundbreaking book, nitric oxide expert Nathan Bryan, PhD, and natural healer Janet Zand, OMD, tell you all about nitric oxide, the miracle molecule that can dramatically improve your health. What the molecule is. How it keeps your arteries young and flexible, regulating blood pressure, and stopping the buildup of artery-clogging plaque. Why most people over 40-years-old have severely diminished levels of NO, and what to do about it. They also show how the molecule works to prevent and treat other chronic conditions, such as diabetes, arthritis, asthma, osteoporosis, and erectile dysfunction. And how it strengthens the immune system and energizes the brain.

The book includes dozens of easy-to-follow tips for increasing NO levels, using NO-boosting foods, supplements, easy exercise, and other natural methods like deep breathing, naps, hot baths, acupuncture--even watching movies that make you laugh

The Nitric Oxide (NO) Solution provides you with the best and simplest solution to the problems of cardiovascular disease, aging, and ill health.

About The Authors Nathan Bryan, PhD is a leading expert on nitric oxide, and assistant professor of molecular medicine at the Brown Foundation Institute of Molecular Medicine of the School of Medicine at the University of Texas Health Science Center in Houston. Janet Zand, OMD, is a doctor of oriental medicine, author of several books on natural healing, and a pioneer in the development of nutritional and herbal supplements. Bill Gottlieb is an author specializing in natural health whose books have sold more than 2 million copies.

As Dr. Nathan Bryan clearly points out, there's one miracle molecule in your body that is largely responsible for your health and longevity...NITRIC OXIDE. -Lou Ignarro, 1998 Nobel Prize Winner in Physiology or Medicine

The Secret of Nitric Oxide by Dr Nathan Bryan may be one of the most important books that you will ever read... -Mark C. Houston, M.D., M.S., M.Sc., Director, Hypertension Institute and Vascular Biology, Saint Thomas Hospital

Dr Bryan masterfully unveils the life-changing potential of nitric oxide, from its Nobel Prize-winning discovery to its transformative role in health and disease... -Robert Lufkin M.D., NYT bestselling author of Lies I Taught In Medical Schooland medical school professor

I enthusiastically endorse this book and urge all who care about health and healthy longevity to read it and incorporate this knowledge into your life... -Felice Gersh, M.D., Medical Director, Integrative Medical Group of Irvine

The remarkable discovery of the molecule nitric oxide or NO back in the early 1980s revolutionized vascular biology and the understanding of chronic disease. Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad won the 1998 Nobel Prize in Physiology or Medicine for their discoveries about nitric oxide. Several years later, one man and his discoveries cracked the code on developing a solid dose form of nitric oxide gas as an oral delivery and also a dual-chamber delivery for topical applications. This book will take the reader through the early life of Dr. Bryan through his education and research that led to these important discoveries and will inspire, motivate and encourage others to follow their dreams and not give up even when it seems the cards are stacked against you.

There is mounting evidence that the established paradigm of nitric oxide (NO) biochemistry, from formation through NO synthases, over interaction with soluble guanylyl cyclase, to eventual disposal as nitrite/nitrate, represents only part of a richer chemistry through which NO elicits biological signalling. Additional pathways have been suggested that include interaction of NO-derived metabolites with thiols and metals to form S-nitrosothiols (RSNOs) and metal nitrosyls. Despite the overwhelming attention paid in this regard to RSNOs, little is known about the stability of these species, their significance outside the circulation, and whether other nitros(yl)ation products are of equal importance. Our study further reveals that all NO-derived products are highly dynamic, have fairly short lifetimes, and are linked to tissue oxygenation and redox state. Moreover, tissue nitrite can serve as a significant extravascular pool of NO during brief periods of hypoxia. These findings vastly expand our understanding of the fate of NO in vivo and provide a framework for further exploration of the significance of nitrosative events in redox-sensing and signaling.